CAS: 94-15-5 Dimethocaine Larocaine Lidocaine Lidocaine hydrochloride Benzocaine Benzocaine hydrochloride Tetracaine Tetracaine hydrochloride Dimethocaine Dimethocaine Hydrochloride Procaine Procaine hydrochloride Prilocaine Bupivacaine tiletamine Propara

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Lidocaine 137-58-6
Lidocaine hydrochloride 73-78-9
Benzocaine 94-09-7
Benzocaine hydrochloride 23239-88-5
Tetracaine 94-24-6
Tetracaine hydrochloride 136-47-0
Dimethocaine 94-15-5
Dimethocaine Hydrochloride 553-63-9
Procaine 59-46-1
Procaine hydrochloride 51-05-8
Prilocaine 721-50-6
Bupivacaine 2180-92-9
tiletamine 14176-49-9
Proparacaine 298-50-0
Dyclonine 586-60-7
Articaine 23964-58-1
Levobupivacaine 27262-47-1
Ropivacaine 84057-95-4



Dimethocaine Basic information
Product Name: Dimethocaine
Synonyms: Dimethocaine;NSC 68927;3-Diethylamino-2,2-dimethylpropyl 4-aminobenzoate;4-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl ester;3-(Diethylamino)-2,2-dimethyl-1-propanol p-aminobenzoate;Larocaine;p-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl;p-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl ester
CAS: 94-15-5
MF: C16H26N2O2
MW: 278.39
EINECS: 1592732-453-0
Product Categories: chemical research;medicine grade;pharmaceutical intermediate;94-15-5
Mol File: 94-15-5.mol
Dimethocaine Structure
Dimethocaine Chemical Properties
Melting point 53.0 to 57.0 °C
Boiling point 421.21°C (rough estimate)
density 1.035
refractive index 1.5290 (estimate)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 10.08±0.25(Predicted)
color Pale Orange to Light Orange
Merck 14,3221
InChIKey OWQIUQKMMPDHQQ-UHFFFAOYSA-N
CAS DataBase Reference 94-15-5
Safety Information
RTECS UB1575000
MSDS Information
Dimethocaine Usage And Synthesis
Description Dimethocaine, also known as DMC or larocaine, is a compound with stimulating effects similar to those of cocaine. It was used in the 1930s as a local anesthetic in dentistry and ophthalmology. Just like cocaine, dimethocaine is addictive due to its stimulation of the reward pathway in the brain. However, dimethocaine is a legal cocaine replacement in some countries and is even listed by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) under the category “synthetic cocaine derivatives”. The structure of dimethocaine, being a 4-aminobenzoic acid ester, resembles that of procaine.
Chemical Properties Dimethocaine is a yellow chrystalline powder. It is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas.
Uses Dimethocaine is a local anesthetic with stimulatory properties that is half the potency of cocaine.
Biological Activity Dimethocaine is a local anesthetic that, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.